Nocicepção térmica em Ratos Tratados com Polpa e Extrato Etanólico de Noni (Morinda citrifolia L.)
نویسندگان
چکیده
The treatment for pain relief is mainly focus on the use of antinociceptive drugs. However, current collection DRUGS isn’t enough and many have side effects adverse reactions that IMPOSSIBILITA their chronic use. Based this problem, article’s aim to evaluate a supposed effect Morinda citrifolia L in rats using hot plate assays (HPA) OBSERVANDO latency time (LT) following groups: control (C); ethanolic pulp extract (EPE) (PE), natura, both noni; ascorbic acid (AA); diazepam (D); morphine (M) association diazepam-morphine (DM). In post-30 min experiments with EPE PE, there was partial increase TL equal observed after 20 PE. interval 30 40 min, moderate tolerance thermal stimulus PE declined showing an tendency. AA group showed nociceptive during first at it similar same time, indicating action. results suggest tendency effects, although not significant, when compared C, having little more pronunced.
منابع مشابه
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ژورنال
عنوان ژورنال: Amazônia
سال: 2022
ISSN: ['1980-5128', '2317-5125']
DOI: https://doi.org/10.18606/2318-1419/amazonia.sci.health.v10n3p26-42